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Thus, the proposed antioxidant mechanism of NAC is not related to the direct scavenging of ROS (superoxide or H 2 O 2 ) or a direct antioxidant mechanism, acting as a substrate for antioxidant enzymes or even as a direct scavenger of drug-derived electrophilic metabolites
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During DSF treatment, alcohol ingestion leads to acetaldehyde accumulation due to ALDH inhibition, causing the DSF-ethanol reaction (Jørgensen et al., 2011)
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