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piUL49 binds to and activates HSV-1 dUTPase To determine the mechanism by which piUL49 regulates HSV-1 virulence and replication in vivo, we investigated the localization of MEF-piUL49 in HSV-1-infected cells
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MS is characterized by damage of myelin associated with infiltrating immune cells and inflammation that leads to progressive axonal degeneration and synaptic loss, coupled with the recruitment of resident microglia to sites of myelin injury (Lassmann, 2001, O’Loughlin et al., 2018)
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