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Lower DSIP levels have been correlated with depressive states, suggesting its involvement in hypothalamic-pituitary-adrenal (HPA) axis modulation ( 11 )
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however, it should be kept in mind that many individuals with ASD have phenol intolerance, and gene analysis should be conducted for the enzymes catecholamine-ortho-methyl transferase (COMT), monoamine oxidase (MAO), and phenol sulfur transferase (PST) that catabolize phenolic compounds
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