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Verify pregnancy status in females of reproductive potential before starting Methotrexate Injection [see Contraindications ( 4) and Warnings and Precautions ( 5.1)]
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This process, known as lipid peroxidation, involves the reaction of polyunsaturated fatty acids (PUFAs) present in cellular membrane phospholipids with oxygen, leading to the formation of lipid hydroperoxides
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