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Numerous aberrant ALS associated proteins can directly interact with mitochondria, compromising their functioning, for instance mutant SOD1 protein accumulates inside mitochondria and impairs energy-generating complexes

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doi: 10.1002/adhm.202001305 [DOI] [PMC free article] [PubMed] [Google Scholar] 352.Moffat KL, Levine WN, Spalazzi JP, Doty SB, Levine WN, Lu HH

site nih.gov l-carnitine treat osteoarthritis alleviates synovitis in knee by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway Peptide therapy, elevated ✨

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